Regenerative Medicine

Ten-Pass Ozone Therapy

High-dose medical ozone delivered across 10 progressive passes — a powerful systemic immune and metabolic intervention.

Ten-pass ozone therapy is a high-dose variant of major autohemotherapy (MAH). In a single session, approximately 200ml of blood is drawn, ozonated, and returned — repeated up to 10 times during the same visit. The total ozone exposure approaches what EBOO delivers but uses a different delivery mechanism. Ten-pass is a powerful tool for chronic immune dysregulation, post-viral fatigue, and select autoimmune presentations.

Ten-pass ozone therapy progressively exposes your circulating blood volume to medical-grade ozone at increasing doses across the 10 passes. The therapeutic mechanism includes upregulation of antioxidant defenses (NRF2 pathway), modulation of inflammatory cytokines, improved oxygen utilization, and immune system rebalancing. Each pass adds to the cumulative effect, with the final passes at the highest tolerated ozone concentration. Total session time is typically 90–120 minutes. Clinical applications include chronic fatigue and post-viral syndromes, Lyme and tick-borne illness recovery, autoimmune dysregulation, athletic recovery, and select cancer adjunct protocols (under separate oncology supervision). Contraindications match standard ozone therapy: G6PD deficiency, hyperthyroidism, recent stroke or MI, pregnancy, and active hemorrhage. Pre-treatment baseline labs are required for first-time patients.

Key Benefits

01Higher total ozone dose than standard single-pass MAH
02Established safety profile — used clinically in Europe for decades
03Single-session systemic effect — no multi-week protocol required
04Strong clinical evidence in chronic fatigue and autoimmune dysregulation
05Performed under physician supervision with continuous monitoring
06Often combined with high-dose vitamin C IV for synergistic antioxidant/oxidant balance

Common Questions

Frequently asked

How is ten-pass different from a regular ozone treatment?

A standard major autohemotherapy (MAH) treats one bag of blood (~200ml) and returns it. Ten-pass repeats this 10 times in the same session at progressively higher ozone concentrations — the total dose approaches what EBOO delivers via a different mechanism.

How long does the session take?

90–120 minutes total. Each pass takes 8–12 minutes including the ozonation step.

Is ten-pass safer than EBOO?

Both are safe when performed by trained physicians. Ten-pass uses simpler equipment and a less complex circuit; EBOO uses continuous filtration. Risk profiles are comparable. Choice typically depends on availability, patient tolerance, and condition being addressed.

What does it feel like?

Most patients describe a warm sensation as ozonated blood returns. No major discomfort. Many feel energized for hours afterward.

How many sessions for chronic conditions?

Series of 4–10 sessions over 2–3 months for chronic Lyme, autoimmune dysregulation, or chronic fatigue, then maintenance every 1–3 months.

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