Regenerative Medicine

EBOO (Extracorporeal Blood Oxygenation & Ozonation)

The ten-pass equivalent — your blood is filtered, oxygenated, and ozonated outside the body, then returned in a single 60-minute session.

EBOO (Extracorporeal Blood Oxygenation and Ozonation) is the most advanced form of medical ozone therapy. Unlike traditional MAH (where 200ml of blood is treated and returned), EBOO continuously cycles your blood through a sterile extracorporeal circuit — filtering, oxygenating, and ozonating up to 1.5–2 liters of blood across a 60–90 minute session. The total ozone exposure is dramatically higher than traditional ozone therapy, producing systemic effects on immune modulation, oxidative stress regulation, and microcirculation.

EBOO uses a sterile, single-use extracorporeal circuit with high-purity medical oxygen and pharmaceutical-grade ozone. During the 60–90 minute treatment, blood is drawn from one IV access, passed through the circuit (where it's filtered, oxygenated, and ozonated), and returned through a second IV. The entire procedure is closed-loop and monitored continuously. Total ozone exposure is approximately equivalent to 10 traditional ten-pass ozone sessions — hence the colloquial term "ten-pass equivalent." Studied applications include chronic Lyme disease and post-Lyme syndrome, post-acute sequelae of viral illness, autoimmune conditions with oxidative stress component, athletic recovery and performance optimization, and chronic fatigue. Contraindications include G6PD deficiency, hyperthyroidism, recent stroke or MI, active hemorrhage, and pregnancy. EBOO is performed only by physicians trained in extracorporeal procedures — at Elements, every session is supervised by clinical staff with the relevant certifications.

Key Benefits

01Highest medical ozone dose available outside research settings
02Continuous extracorporeal circuit — your blood passes through dialysis-grade filtration during treatment
03Single session vs 10 traditional MAH sessions
04Studied for chronic fatigue, autoimmune dysregulation, post-viral conditions, athletic recovery
05Improves erythrocyte deformability and tissue oxygen delivery
06Performed in-clinic by trained physicians under continuous monitoring

Common Questions

Frequently asked

What is the difference between EBOO and ten-pass ozone?

EBOO uses a continuous extracorporeal circuit — your blood passes through dialysis-grade filtration during a 60–90 minute treatment, with much higher total ozone exposure. Ten-pass ozone is a series of 10 progressive autohemotherapy passes within the same session. Both are high-dose; EBOO is the more intensive of the two.

What conditions does EBOO treat?

Most-studied applications: chronic Lyme and post-Lyme syndrome, post-acute sequelae of viral illness, autoimmune conditions with oxidative stress component, athletic recovery, and chronic fatigue. We also see use in select cancer adjunct protocols under separate oncology supervision.

How long does an EBOO session take?

Total time is typically 90–120 minutes including IV access, the treatment itself (60–90 minutes), and post-treatment monitoring.

Is EBOO safe?

Yes, when performed by trained physicians under continuous monitoring with sterile single-use equipment. Contraindications include G6PD deficiency, hyperthyroidism, recent stroke or MI, active hemorrhage, and pregnancy. Pre-treatment baseline labs are required for first-time patients.

How many sessions are needed?

Depends on the condition. Acute applications (recovery, performance) often single-session. Chronic conditions often benefit from a series of 4–8 sessions over 2–3 months, then maintenance every 2–3 months.

What does it feel like?

Most patients describe the treatment as resting comfortably with two IVs in place. Energy and mental clarity often improve during or immediately after the session.

← PreviousKnee Stem Cell TherapyNext →Ten-Pass Ozone Therapy

Start here

Book now to talk through whether eboo (extracorporeal blood oxygenation & ozonation) is the right fit for your goals, timeline, and recovery plan.

Book now →

Related Protocols